Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29425558 | 0.91 | KMT2A (0.70) | KMT2AMEN1ALDH1A1TDP1CA1 | |
| SCHEMBL17278 | 0.91 | KMT2A (0.70) | KMT2AMEN1ALDH1A1TDP1CA1 | |
| SCHEMBL11598452 | 0.90 | KMT2A (0.56) | KMT2AMEN1ALDH1A1HSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL7006367 | 0.89 | KMT2A (0.68) | KMT2AMEN1ALDH1A1TDP1CA1 | |
| Methane SCHEMBL9273303 | 0.89 | KMT2A (0.68) | KMT2AMEN1ALDH1A1TDP1CA1 | |
| Nitrobenzene SCHEMBL29117067 | 0.86 | KMT2A (0.59) | KMT2AMEN1ALDH1A1CA1CA2 | |
| Hydroxyamine SCHEMBL28312301 | 0.86 | KMT2A (0.63) | KMT2AMEN1ALDH1A1TDP1CA1 | |
| SCHEMBL28509315 | 0.84 | KMT2A (0.51) | KMT2AMEN1ALDH1A1CA1CA2 | |
| SCHEMBL8725803 | 0.83 | KMT2A (0.51) | KMT2AMEN1ALDH1A1CA1CA2 | |
| SCHEMBL2041279 | 0.80 | KMT2A (1.00) | KMT2AMEN1ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744597-A | Stereoselective anion glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides | ELI LILLY AND COMPANY (US) | 1998-04-28 | — | — | US | disclosed |