Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.44 |
| ▸ | HTR2A | P28223 | 6/20 | 0.44 |
| ▸ | HTR2B | P41595 | 6/20 | 0.44 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13198401 | 0.82 | HTR2C (0.62) | HTR2CHTR2AHTR2B | |
| SCHEMBL412687 | 0.80 | UGT2B17 (0.56) | UGT2B17 | |
| SCHEMBL19827774 | 0.74 | HTR2A (0.35) | HTR2CHTR2AHTR2B | |
| SCHEMBL20368645 | 0.73 | HTR2A (0.44) | HTR2CHTR2AHTR2BUGT2B17 | |
| SCHEMBL14444122 | 0.71 | HTR2C (0.41) | HTR2CHTR2AHTR2BNOTUM | |
| SCHEMBL24542980 | 0.69 | UGT2B17 (0.41) | HTR2CHTR2AHTR2BUGT2B17NOTUM | |
| SCHEMBL29673089 | 0.69 | UGT2B17 (0.41) | HTR2CHTR2AHTR2BUGT2B17NOTUM | |
| SCHEMBL14543582 | 0.68 | UGT2B17 (0.44) | HTR2CHTR2AHTR2BUGT2B17 | |
| SCHEMBL20368603 | 0.68 | HTR2A (0.42) | HTR2CHTR2AHTR2B | |
| SCHEMBL15822109 | 0.67 | UGT2B17 (0.35) | HTR2CHTR2AHTR2BUGT2B17NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760839-B1 | PYRIDINEDIONE CARBOXAMIDE INHIBITORS OF ENDOTHELIAL LIPASE | BRISTOL MYERS SQUIBB CO (US) | 2015-11-25 | — | — | EP | disclosed |