SCHEMBL15822109

SCHEMBL15822109

Cc1cc(Cl)c2c(c1)C(O)C(C)C2

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
UGT2B17 O75795 2/20 0.35
HTR2A P28223 2/20 0.31
HTR2C P28335 2/20 0.31
HTR2B P41595 2/20 0.31
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2044938 0.81 UGT2B17 (0.49) UGT2B17
SCHEMBL15821768 0.76 SLC9A3 (0.30) HTR2AHTR2CHTR2B
SCHEMBL20634836 0.76 SLC9A3 (0.30) HTR2AHTR2CHTR2B
SCHEMBL29392659 0.76 SLC9A3 (0.30) HTR2AHTR2CHTR2B
SCHEMBL21451141 0.76 SLC9A3 (0.30) HTR2AHTR2CHTR2B
SCHEMBL22246617 0.72 HTR2A (0.33) UGT2B17HTR2AHTR2CHTR2B
SCHEMBL17278091 0.67 HTR2C (0.44) UGT2B17HTR2AHTR2CHTR2BNOTUM
SCHEMBL3664467 0.67
SCHEMBL14784874 0.66 HCAR2 (0.34) HTR2AHTR2C
SCHEMBL19827774 0.64 HTR2A (0.35) HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11981801-B2 Polypropylene composition BOREALIS AG (AT) 2024-05-14 US disclosed
US-20230242748-A1 POLYPROPYLENE COMPOSITION BOREALIS AG (AT) 2023-08-03 US disclosed
CN-110770264-B Process for preparing heterophasic propylene copolymers 博里利斯股份公司 2022-10-14 CN disclosed
CN-110177798-B Catalyst and process for preparing same 博里利斯股份公司 2022-08-30 CN disclosed
US-11352376-B2 Catalysts BOREALIS AG (AT) 2022-06-07 US disclosed
CN-110741039-B Polypropylene composition 博里利斯股份公司 2022-02-18 CN disclosed
US-11078304-B2 Process for preparing heterophasic propylene copolymers BOREALIS AG (AT) 2021-08-03 US disclosed
EP-3541823-B1 CATALYSTS BOREALIS AG (AT) 2020-12-30 EP disclosed
EP-3652247-A1 POLYPROPYLENE COMPOSITION Borealis AG (AT) 2020-05-20 EP disclosed
EP-3649162-A1 PROCESS FOR PREPARING HETEROPHASIC PROPYLENE COPOLYMERS Borealis AG (AT) 2020-05-13 EP disclosed
EP-3541823-A1 CATALYSTS Borealis AG (AT) 2019-09-25 EP disclosed
WO-2019012110-A1 POLYPROPYLENE COMPOSITION BOREALIS AG (AT) 2019-01-17 WO disclosed
WO-2019007655-A1 PROCESS FOR PREPARING HETEROPHASIC PROPYLENE COPOLYMERS BOREALIS AG (AT) 2019-01-10 WO disclosed
WO-2018091684-A1 CATALYSTS BOREALIS AG (AT) 2018-05-24 WO disclosed
WO-2018091684-A1 CATALYSTS BOREALIS AG (AT) 2018-05-24 WO disclosed
EP-3301098-A1 PROCESS FOR THE PREPARATION OF A LIGAND FOR A CATALYST Borealis AG (AT) 2018-04-04 EP disclosed
EP-2935296-B1 CATALYST BOREALIS AG (AT) 2017-11-15 EP disclosed
US-20150329653-A1 CATALYST BOREALIS AG (AT) 2015-11-19 US disclosed
EP-2935296-A1 CATALYST Borealis AG (AT) 2015-10-28 EP disclosed
WO-2014096282-A1 CATALYST BOREALIS AG (AT) 2014-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11352376-B2 Catalysts SIGMAR1, H1-2, SFN UGT2B17 3744/4885HTR2A 1980/4885HTR2C 723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.