SCHEMBL17278136

SCHEMBL17278136

BC(CCCC)CCCCCCCC

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.52
TSHR P16473 1/20 0.47
THRB P10828 1/20 0.47
LMNA P02545 1/20 0.46
LCK P06239 1/20 0.44
PPARD Q03181 1/20 0.44
ZDHHC20 Q5W0Z9 1/20 0.44
ZDHHC2 Q9UIJ5 1/20 0.44
OPRM1 P35372 1/20 0.43
CA2 P00918 1/20 0.43
GPR84 Q9NQS5 3/20 0.41
FDPS P14324 3/20 0.41
SPHK1 Q9NYA1 1/20 0.41
FFAR1 O14842 1/20 0.41
ZDHHC7 Q9NXF8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12807713 1.00 DNM1 (0.52) DNM1TSHRTHRBLMNALCK
SCHEMBL8281377 1.00 DNM1 (0.52) DNM1TSHRTHRBLMNALCK
SCHEMBL10064927 0.97 DNM1 (0.48) DNM1TSHRTHRBLMNALCK
SCHEMBL12807719 0.97 DNM1 (0.48) DNM1TSHRTHRBLMNALCK
SCHEMBL17787405 0.97 TSHR (0.50) DNM1TSHRTHRBLMNALCK
SCHEMBL19069927 0.97 TSHR (0.50) DNM1TSHRTHRBLMNALCK
SCHEMBL14639891 0.97 TSHR (0.50) DNM1TSHRTHRBLMNALCK
SCHEMBL14641771 0.97 TSHR (0.50) DNM1TSHRTHRBLMNALCK
SCHEMBL22698780 0.97 TSHR (0.50) DNM1TSHRTHRBLMNALCK
SCHEMBL8272324 0.97 TSHR (0.50) DNM1TSHRTHRBLMNALCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2947066-A1 PHENOXYALKYLAMINE COMPOUND Osaka University (JP) 2015-11-25 EP disclosed