Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.54 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.46 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.46 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.46 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601920 | 0.96 | MEN1 (0.78) | MEN1KMT2AHTTPHLPP2PTPN1 | |
| SCHEMBL18784959 | 0.91 | MEN1 (0.85) | MEN1KMT2AHTTPHLPP2PTPN1 | |
| SCHEMBL14664307 | 0.88 | MEN1 (0.79) | MEN1KMT2AHTTPHLPP2PTPN1 | |
| SCHEMBL16601542 | 0.84 | MEN1 (0.73) | MEN1KMT2AHTTPHLPP2PTPN1 | |
| Trypan Blue Free Acid SCHEMBL29415031 | 0.83 | MEN1 (1.00) | MEN1KMT2AHTTPHLPP2PTPN1 | |
| Trypan Blue Free Acid SCHEMBL12234090 | 0.83 | MEN1 (1.00) | MEN1KMT2AHTTPHLPP2PTPN1 | |
| Trypan Blue Free Acid SCHEMBL29376676 | 0.83 | MEN1 (1.00) | MEN1KMT2AHTTPHLPP2PTPN1 | |
| Trypan Blue Free Acid SCHEMBL15497820 | 0.83 | MEN1 (1.00) | MEN1KMT2AHTTPHLPP2PTPN1 | |
| Trypan Blue Free Acid SCHEMBL29355441 | 0.83 | MEN1 (1.00) | MEN1KMT2AHTTPHLPP2PTPN1 | |
| SCHEMBL15397120 | 0.82 | MEN1 (0.64) | MEN1KMT2AHTTPHLPP2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150338417-A1 | BINDING DOMAIN MAPPING | GEORGE MASON UNIVERSITY | 2015-11-26 | — | — | US | disclosed |