Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14186271 | 1.00 | TDP1 (0.31) | TDP1 | |
| SCHEMBL10209001 | 1.00 | TDP1 (0.31) | TDP1 | |
| SCHEMBL12269509 | 0.96 | TDP1 (0.32) | TDP1 | |
| SCHEMBL14186221 | 0.94 | — | — | |
| SCHEMBL10208802 | 0.94 | — | — | |
| SCHEMBL14970039 | 0.94 | — | — | |
| SCHEMBL10208864 | 0.94 | APLNR (0.31) | — | |
| SCHEMBL10266072 | 0.93 | — | — | |
| SCHEMBL14186192 | 0.93 | — | — | |
| SCHEMBL10265384 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768966-B1 | COUMPOUNDS AND METHODS FOR INHIBITING THE INTERACTION OF BCL PROTEINS WITH BINDING PARTNERS | INFINITY DISCOVERY INC (US) | 2012-03-07 | — | — | EP | disclosed |