Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR5 | P32302 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.40 |
| ▸ | FEN1 | P39748 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 6/20 | 0.40 |
| ▸ | CNR2 | P34972 | 5/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950631 | 0.83 | HTR2C (0.42) | HTR2CHTR1ASLC6A2SLC6A4KCNH2 | |
| SCHEMBL16951549 | 0.77 | HTR2C (0.46) | ALOX5APFEN1HTR2CHTR1ASLC6A2 | |
| SCHEMBL16892421 | 0.75 | HTR2C (0.44) | HTR2CHTR1ASLC6A2SLC6A4OPRL1 | |
| SCHEMBL4441546 | 0.73 | KDM4E (0.54) | HTR2CHTR1ASLC6A2SLC6A4RIPK1 | |
| SCHEMBL27248573 | 0.73 | CXCR5 (0.60) | CXCR5 | |
| SCHEMBL6877898 | 0.72 | PDE4B (0.43) | CXCR5HTR1ASLC6A2SLC6A4RIPK1 | |
| SCHEMBL28230560 | 0.72 | HTR2C (0.58) | HTR2CCNR2HTR1ASLC6A2SLC6A4 | |
| SCHEMBL16892468 | 0.71 | HTR2C (0.41) | HTR2CHTR1ASLC6A2SLC6A4 | |
| SCHEMBL28308046 | 0.71 | SLC6A2 (0.54) | HTR2CHTR1ASLC6A2SLC6A4 | |
| SCHEMBL16961400 | 0.71 | HTR1A (0.42) | HTR2CHTR1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | disclosed |