Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NR2E1 | Q9Y466 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17280574 | 0.86 | CYP2D6 (0.53) | CYP2D6TSHRMAPK1NR2E1KDM4E | |
| SCHEMBL17280580 | 0.82 | CYP2D6 (0.49) | CYP2D6TSHRNR2E1KDM4ECYP1A2 | |
| SCHEMBL26425959 | 0.81 | CYP2D6 (0.58) | CYP2D6TSHRMAPK1NR2E1KDM4E | |
| SCHEMBL28680552 | 0.80 | CYP2D6 (1.00) | CYP2D6TSHRMAPK1NR2E1KDM4E | |
| SCHEMBL28680554 | 0.80 | CYP2D6 (1.00) | CYP2D6TSHRMAPK1NR2E1KDM4E | |
| SCHEMBL27902832 | 0.79 | CYP1A2 (0.55) | CYP2D6TSHRMAPK1NR2E1KDM4E | |
| Hydrochloric Acid SCHEMBL11231352 | 0.79 | CYP2D6 (0.98) | CYP2D6TSHRMAPK1NR2E1KDM4E | |
| SCHEMBL23896249 | 0.79 | CYP2D6 (0.57) | CYP2D6TSHRMAPK1NR2E1KDM4E | |
| SCHEMBL13572916 | 0.78 | TSHR (0.76) | TSHRMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL12879452 | 0.77 | CYP2D6 (0.56) | CYP2D6TSHRKDM4ECYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9534140-B2 | Resist underlayer film-forming composition | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-01-03 | — | — | US | disclosed |
| US-20150337164-A1 | RESIST UNDERLAYER FILM-FORMING COMPOSITION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-11-26 | — | — | US | disclosed |