SCHEMBL17280686

SCHEMBL17280686

CCc1c(Cn2c3ccccc3c3ccccc32)ccc2c1Cc1ccccc1-2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.38
CYP19A1 P11511 1/20 0.36
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
DRD2 P14416 1/20 0.34
DRD4 P21917 1/20 0.34
DRD3 P35462 1/20 0.34
KDR P35968 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CNR2 P34972 1/20 0.32
POLB P06746 1/20 0.32
ALDH1A1 P00352 2/20 0.32
PGR P06401 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17694998 0.82 CYP19A1 (0.36) CYP19A1NPC1RAB9ADRD2DRD4
SCHEMBL16805477 0.81 PNMT (0.55) PNMTCYP19A1NPC1RAB9ADRD2
SCHEMBL17694996 0.81 KDR (0.38) CYP19A1KDRCYP1A2CYP2C19CA1
SCHEMBL17280673 0.81 KDR (0.38) CYP19A1KDRCYP1A2CYP2C19CA1
SCHEMBL3485944 0.80 PNMT (0.49) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL16805468 0.78 PNMT (0.46) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL16805466 0.78 PNMT (0.46) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL16805467 0.77 PNMT (0.43) PNMTCYP19A1NPC1RAB9ADRD2
SCHEMBL16805469 0.77 TP53 (0.44) PNMTDRD2DRD4DRD3CNR2
SCHEMBL17694997 0.76 CYP19A1 (0.42) PNMTCYP19A1NPC1RAB9ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732069-B2 Carbazole compound and organic light emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-08-15 US disclosed
US-20150336937-A1 CARBAZOLE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150336937-A1 CARBAZOLE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCUDING THE SAME CYP1B1, CCNT1, CHRM1 PNMT 2772/4885CYP19A1 251/4885NPC1 3363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.