Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LSS | P48449 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
| ▸ | FABP6 | P51161 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17276522 | 0.90 | HRH3 (0.44) | HRH3ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL17276462 | 0.89 | ALDH1A1 (0.45) | HRH3ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL17276280 | 0.87 | KDM4E (0.45) | HRH3ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL17276719 | 0.81 | HRH3 (0.47) | HRH3ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL17276358 | 0.77 | ALDH1A1 (0.61) | HRH3ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL17276591 | 0.76 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTTSHRMAPK1 | |
| SCHEMBL17276744 | 0.75 | LSS (0.53) | ALDH1A1KDM4ELSSMEN1KMT2A | |
| SCHEMBL17276378 | 0.74 | LSS (0.54) | ALDH1A1KDM4ELSSMEN1KMT2A | |
| SCHEMBL17276478 | 0.73 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTTSHRMAPK1 | |
| SCHEMBL17276477 | 0.72 | LSS (0.54) | ALDH1A1KDM4ELSSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015179559-A2 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABIDE THERAPEUTICS, INC. (US) | 2015-11-26 | — | — | WO | disclosed |