Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | FABP1 | P07148 | 1/20 | 0.52 |
| ▸ | FABP6 | P51161 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17281600 | 0.91 | KDM4E (0.60) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL17281577 | 0.83 | KDM4E (0.62) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL17281587 | 0.83 | KDM4E (0.62) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL17281608 | 0.82 | KDM4E (0.61) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL94838 | 0.75 | MEN1 (0.72) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL8925693 | 0.73 | ALDH1A1 (0.75) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL12058759 | 0.73 | KMT2A (0.75) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL19078745 | 0.73 | HTT (0.59) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL17276341 | 0.73 | LSS (0.51) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL16598448 | 0.72 | KDM4E (0.66) | KDM4ETDP1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015179559-A2 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABIDE THERAPEUTICS, INC. (US) | 2015-11-26 | — | — | WO | disclosed |