Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.45 |
| ▸ | RELA | Q04206 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 11/20 | 0.44 |
| ▸ | GAA | P10253 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 8/20 | 0.40 |
| ▸ | NPC1 | O15118 | 7/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24545437 | 0.96 | KDM4E (0.42) | KDM4ESMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL15773491 | 0.89 | KDM4E (0.42) | KDM4ESMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL24550398 | 0.89 | KDM4E (0.46) | KDM4ESMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL15773494 | 0.89 | KDM4E (0.40) | KDM4ESMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL24553434 | 0.89 | KDM4E (0.40) | KDM4ESMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL24553404 | 0.88 | KDM4E (0.41) | KDM4ESMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL24553086 | 0.88 | KDM4E (0.38) | KDM4ESMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL24552090 | 0.88 | KDM4E (0.43) | KDM4ESMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL24550582 | 0.88 | KDM4E (0.39) | KDM4ESMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL24551757 | 0.88 | KDM4E (0.39) | KDM4ESMN1; SMN2NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2926385-B1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2020-08-05 | — | — | EP | disclosed |
| US-20150336959-A1 | Electronic Device | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
| US-20150336959-A1 | Electronic Device | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336959-A1 | Electronic Device | ETFB, ETFA, XPOT | KDM4E 3240/4885SMN1; SMN2 2933/4885NFKB1 3753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.