ETFB

Electron transfer flavoprotein subunit beta · P38117 · ETFB on Sugi Atlas →

453 patent compounds predicted against ETFB, 312 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Crenolanib (SCHEMBL2730601)	1.00	1/20
Crenolanib (SCHEMBL29350134)	1.00	1/20
Crenolanib (SCHEMBL29352568)	1.00	1/20
Crenolanib (SCHEMBL30002138)	1.00	1/20
SCHEMBL22567082	0.86	1/20
SCHEMBL5662568	0.85	1/20
Crenolanib (SCHEMBL4681285)	0.85	1/20
Crenolanib (SCHEMBL29352554)	0.85	1/20
Crenolanib (SCHEMBL29361948)	0.85	1/20
SCHEMBL27030604	0.85	1/20
SCHEMBL30775111	0.85	1/20
SCHEMBL23026363	0.82	1/20
SCHEMBL3191766	0.80	1/20
SCHEMBL27030775	0.80	1/20
SCHEMBL30441378	0.80	1/20
SCHEMBL3180117	0.79	1/20
SCHEMBL3189249	0.78	1/20
SCHEMBL3190082	0.78	1/20
SCHEMBL3190135	0.78	1/20
SCHEMBL3182258	0.76	1/20

Clinical trials — most relevant to ETFB by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Clinical Evaluation of the Effect of Metformin in Sepsis	PHASE3	UNKNOWN
A Study of Efficacy, Safety and Tolerability of Idebenone in the Treatment of Friedreich's Ataxia (FRDA) Patients	PHASE3	COMPLETED
Effect of Pioglitazone Administered to Patients With Friedreich's Ataxia: Proof of Concept	PHASE3	COMPLETED
Effect of Bezafibrate on Muscle Metabolism in Patients With Fatty Acid Oxidation Defects	PHASE2	COMPLETED
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
Metabolic Cofactor Supplementation in Obese Patients With Non-Alcoholic Fatty Liver Disease	PHASE2	COMPLETED
Metabolic Cofactor Supplementation in Alzheimer's Disease (AD) and Parkinson's Disease (PD) Patients	PHASE2	COMPLETED
Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy	PHASE2	ACTIVE_NOT_RECRUITING
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
Melatonin in Healthy Volunteers	PHASE1	COMPLETED
NCF Gene & TNFSF4 in SLE Patients	nan	UNKNOWN
Apoptosis Markers in Aggressive Periodontitis	nan	COMPLETED
Transcranial Photobiomodulation for the Treatment of Pediatric Depression	nan	WITHDRAWN
Pathogenesis of Acute Stress Induced (Tako-tsubo) Cardiomyopathy: Energy Shut-Down or Intense Inflammation?	nan	COMPLETED
Relationship Between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy	nan	COMPLETED
Mitoquines in COPD	nan	UNKNOWN
Resistance Exercise in Barth Syndrome	nan	COMPLETED
Exercise-mediated Rescue of Mitochondrial Dysfunctions Driving Insulin Resistance	nan	COMPLETED
Physical Activity Following Surgery Induced Weight Loss	nan	COMPLETED
Effect Inhaled Nitric Oxide in Adult Liver Transplant	nan	NOT_YET_RECRUITING
Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea	nan	RECRUITING
TranspulmonarY Estrogen Gradient and Estrogen Receptors (TYEGER) in PAH	nan	WITHDRAWN
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
Mitochondrial Function of Immune Cells in Sepsis	nan	COMPLETED
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
Nutraceutical Composition Containing Natural Products Derivatives on the Modulation of the Endocrine Neuroimmune Axis	nan	COMPLETED
Natural History Study of FDXR Mutation-related Mitochondriopathy	nan	COMPLETED
Fatty Acid Metabolism and Insulin Sensitivity: the Role of Endurance Exercise	nan	COMPLETED
Fatty Acid Oxidation Defects and Insulin Sensitivity	nan	COMPLETED
Parkinson's Diseases Susceptibility Genes and Pesticides	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a ETFB binder may also engage these)

Protein	Name	Similarity
Q68FU3	—	1.000	Q68FU3 →
Q9DCW4	—	1.000	Q9DCW4 →
Q6UAQ8	—	1.000	Q6UAQ8 →
Q5RFK0	—	1.000	Q5RFK0 →
Q2TBV3	—	0.999	Q2TBV3 →
P38975	—	0.999	P38975 →
P53575	—	0.998	P53575 →
Q9LSW8	—	0.995	Q9LSW8 →
Q54YZ4	—	0.995	Q54YZ4 →
Q9UTH2	—	0.990	Q9UTH2 →
P42940	—	0.989	P42940 →
A2XQV4	—	0.988	A2XQV4 →
P53576	—	0.988	P53576 →
Q7F9U3	—	0.987	Q7F9U3 →
P26482	—	0.987	P26482 →
O33095	—	0.986	O33095 →
Q57770	—	0.985	Q57770 →
H6LBB0	—	0.984	H6LBB0 →
Q9V2T8	—	0.984	Q9V2T8 →
O29871	—	0.983	O29871 →
A8MAJ1	—	0.983	A8MAJ1 →
P97089	—	0.983	P97089 →
P28488	—	0.983	P28488 →
Q7NUC2	—	0.983	Q7NUC2 →
Q8PV87	—	0.983	Q8PV87 →
A3DKB6	—	0.983	A3DKB6 →
Q9C4Z0	—	0.982	Q9C4Z0 →
Q0AZ34	—	0.982	Q0AZ34 →
A7I6S6	—	0.982	A7I6S6 →
A1AZH7	—	0.982	A1AZH7 →