SCHEMBL1728256

SCHEMBL1728256

C=C(F)CN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3914315 0.96
SCHEMBL18198523 0.72
SCHEMBL491178 0.70
SCHEMBL1954609 0.70
SCHEMBL21455454 0.68
SCHEMBL722774 0.67
SCHEMBL1591041 0.67
SCHEMBL1261724 0.67
SCHEMBL20483096 0.67
SCHEMBL6014450 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12162871-B2 Inhibitors of VAP-1 ACUCELA INC. (US) 2024-12-10 US disclosed
US-11916195-B2 Electrolyte solution, electrochemical device, lithium ion secondary battery, and module DAIKIN INDUSTRIES, LTD. (JP) 2024-02-27 US disclosed
US-11787791-B2 Inhibitors of VAP-1 ACUCELA INC. (US) 2023-10-17 US disclosed
US-11787791-B2 Inhibitors of VAP-1 ACUCELA INC. (US) 2023-10-17 US disclosed
US-20230295140-A1 INHIBITORS OF VAP-1 ACUCELA INC. 2023-09-21 US disclosed
US-20230295140-A1 INHIBITORS OF VAP-1 ACUCELA INC. 2023-09-21 US disclosed
US-20210387975-A1 INHIBITORS OF VAP-1 ACUCELA INC. 2021-12-16 US disclosed
CN-113164454-A Inhibitors of VAP-1 奥克塞拉有限公司 2021-07-23 CN disclosed
EP-3611166-A1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT Mitsui Chemicals Agro, Inc. (JP) 2020-02-19 EP disclosed
WO-2015175845-A1 BENZIMIDAZOLE DERIVATIVES AND USES THEREOF PELOTON THERAPEUTICS, INC. (US) 2015-11-19 WO disclosed
US-20100247543-A1 TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES ORYZON GENOMICS, S.A. (ES) 2010-09-30 US disclosed
EP-2014285-B1 NPYY5 antagonists SHIONOGI & CO (JP) 2010-05-05 EP disclosed
EP-1202973-B1 PREPARATION OF COMPOUNDS USEFUL FOR THE DETECTION OF HYPOXIA UNIV PENNSYLVANIA (US) 2009-12-30 EP disclosed
EP-2098514-A1 Preparation of compounds useful for the detection of hypoxia THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2009-09-09 EP disclosed
US-7432295-B2 Preparation of compounds useful for the detection of hypoxia THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2008-10-07 US disclosed
US-7230115-B1 Preparation of compounds useful for the detection of hypoxia THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2007-06-12 US disclosed
US-20060159618-A1 Preparation of compounds useful for the detection of hypoxia THE UNIVERSITY OF PENNSYLVANIA 2006-07-20 US disclosed
EP-1202973-A4 PREPARATION OF COMPOUNDS USEFUL FOR THE DETECTION OF HYPOXIA UNIV PENNSYLVANIA (US) 2004-08-18 EP disclosed
EP-1202973-A1 PREPARATION OF COMPOUNDS USEFUL FOR THE DETECTION OF HYPOXIA THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2002-05-08 EP disclosed
WO-2001007414-A1 PREPARATION OF COMPOUNDS USEFUL FOR THE DETECTION OF HYPOXIA THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2001-02-01 WO disclosed