Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 11/20 | 0.69 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15689398 | 0.87 | KIT (0.70) | KITMAP4K4KCNH2SMARCA2SMARCA4 | |
| SCHEMBL15689394 | 0.82 | KIT (1.00) | KIT | |
| SCHEMBL21170671 | 0.82 | KIT (0.48) | KIT | |
| SCHEMBL2272116 | 0.81 | KIT (0.62) | KITPDGFRB | |
| SCHEMBL30945074 | 0.81 | KIT (0.64) | KITJAK3 | |
| SCHEMBL28367516 | 0.81 | KIT (0.64) | KITJAK3 | |
| SCHEMBL5067873 | 0.80 | KIT (0.55) | KITMAP4K4KCNH2SMARCA2SMARCA4 | |
| SCHEMBL15516007 | 0.79 | KIT (0.70) | KITPDGFRB | |
| SCHEMBL14782331 | 0.79 | MAP4K4 (0.57) | KITMAP4K4KCNH2SMARCA2SMARCA4 | |
| SCHEMBL2253309 | 0.79 | AKT1 (0.57) | KITMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015178955-A1 | SUBSTITUTED ETHYNYL HETEROBICYCLIC COMPOUNDS AS TYROSINE KINASE INHIBITORS | Eternity Bioscience Inc. (US) | 2015-11-26 | — | — | WO | disclosed |