Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17282985 | 0.82 | KIT (0.69) | KIT | |
| SCHEMBL15689398 | 0.69 | KIT (0.70) | KIT | |
| SCHEMBL31706572 | 0.65 | JAK3 (0.42) | KIT | |
| SCHEMBL15689394 | 0.65 | KIT (1.00) | KIT | |
| SCHEMBL2272116 | 0.63 | KIT (0.62) | KIT | |
| SCHEMBL4467935 | 0.62 | RIPK1 (0.64) | KIT | |
| SCHEMBL15516007 | 0.62 | KIT (0.70) | KIT | |
| SCHEMBL30945074 | 0.62 | KIT (0.64) | KIT | |
| SCHEMBL5067873 | 0.61 | KIT (0.55) | KITLIMK2 | |
| SCHEMBL5278122 | 0.61 | LMNA (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145512-B1 | SUBSTITUTED ETHYNYL HETEROBICYCLIC COMPOUNDS AS TYROSINE KINASE INHIBITORS | JIANGSU HENGRUI MEDICINE CO (CN) | 2019-07-17 | — | — | EP | disclosed |