SCHEMBL17283345

SCHEMBL17283345

CC1(C)c2ccccc2N(c2nc3cc4oc(-c5ccccc5)nc4cc3o2)c2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 11/20 0.52
RAB9A P51151 11/20 0.52
SMN1; SMN2 Q16637 10/20 0.52
KDM4E B2RXH2 7/20 0.52
HPGD P15428 5/20 0.52
CASP3 P42574 3/20 0.52
SENP7 Q9BQF6 3/20 0.52
SENP6 Q9GZR1 3/20 0.52
POLB P06746 2/20 0.52
SENP8 Q96LD8 2/20 0.52
ALDH1A1 P00352 7/20 0.42
TP53 P04637 3/20 0.42
HSD17B10 Q99714 3/20 0.42
MAPT P10636 4/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
NFKB1 P19838 2/20 0.39
NFKB2 Q00653 2/20 0.39
RELA Q04206 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17283248 0.90 KDM4E (0.35) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17283346 0.88 NPC1 (0.49) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL18680448 0.87 SMN1; SMN2 (0.45) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17283237 0.85 NPC1 (0.45) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17283336 0.84 SMN1; SMN2 (0.52) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17283333 0.82 SMN1; SMN2 (0.50) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17404427 0.81 NPC1 (0.44) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL18680446 0.81 SMN1; SMN2 (0.50) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17283330 0.81 SMN1; SMN2 (0.49) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL18680455 0.80 NPC1 (0.43) NPC1RAB9ASMN1; SMN2KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency UDC IRELAND LTD (IE) 2023-11-23 US disclosed
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency UDC IRELAND LTD (IE) 2023-11-23 US disclosed
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency UDC IRELAND LIMITED (IE) 2023-07-18 US disclosed
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency UDC IRELAND LIMITED (IE) 2023-07-18 US disclosed
US-20200259100-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency UDC IRELAND LTD (IE) 2020-08-13 US disclosed
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency BASF SE (DE) 2017-03-30 US disclosed
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency BASF SE (DE) 2017-03-30 US disclosed
WO-2015176981-A1 FLUORESCENT ORGANIC LIGHT EMITTING ELEMENTS HAVING HIGH EFFICIENCY BASF SE (DE) 2015-11-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 NPC1 2870/4885RAB9A 1728/4885SMN1; SMN2 2504/4885
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency TEAD1, TEAD2, TEAD4 NPC1 2870/4885RAB9A 1728/4885SMN1; SMN2 2504/4885
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 NPC1 2870/4885RAB9A 1728/4885SMN1; SMN2 2504/4885
US-20200259100-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 NPC1 2870/4885RAB9A 1728/4885SMN1; SMN2 2504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.