Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17284520 | 1.00 | HRH4 (0.30) | HRH4 | |
| SCHEMBL13849461 | 0.83 | CHRNA7 (0.33) | HRH4 | |
| SCHEMBL23267575 | 0.83 | CHRNA7 (0.33) | HRH4 | |
| SCHEMBL2271063 | 0.83 | CHRNA7 (0.33) | HRH4 | |
| SCHEMBL21574872 | 0.83 | — | — | |
| SCHEMBL20384070 | 0.82 | HRH3 (0.33) | — | |
| SCHEMBL17284486 | 0.82 | HRH3 (0.33) | — | |
| SCHEMBL17284464 | 0.82 | NCF1 (0.39) | — | |
| SCHEMBL17284574 | 0.82 | NCF1 (0.39) | — | |
| SCHEMBL20384028 | 0.75 | NCF1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022090481-A1 | SUBSTITUTED 1H-PYRAZOLO[4,3-C]PYRIDINES AND DERIVATIVES AS EGFR INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2022-05-05 | — | — | WO | disclosed |
| WO-2020119739-A1 | 2-AMINOPYRIMIDINE COMPOUND AND APPLICATION THEREFOR | 暨南大学 | 2020-06-18 | — | — | WO | disclosed |
| WO-2015177326-A1 | 5-CHLORO-2-DIFLUOROMETHOXYPHENYL PYRAZOLOPYRIMIDINE COMPOUNDS WHICH ARE JAK INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-11-26 | — | — | WO | disclosed |