SCHEMBL17284337

SCHEMBL17284337

CC(C)(C)c1cccc(-c2cccc(C(CC(=O)O)c3nccs3)c2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CTSA P10619 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17284357 0.87 CTSA (1.00) CTSA
SCHEMBL16109147 0.85 CTSA (1.00) CTSA
SCHEMBL16109146 0.85 CTSA (1.00) CTSA
SCHEMBL18813178 0.85 CTSA (1.00) CTSA
SCHEMBL17284382 0.85 CTSA (1.00) CTSA
SCHEMBL17284383 0.84 CTSA (0.88) CTSA
SCHEMBL17284276 0.83 CTSA (1.00) CTSA
SCHEMBL17284333 0.82 CTSA (1.00) CTSA
SCHEMBL17284408 0.82 CTSA (1.00) CTSA
SCHEMBL17284406 0.82 CTSA (1.00) CTSA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9199947-B2 Biaryl-propionic acid derivatives and their use as pharmaceuticals SANOFI (FR) 2015-12-01 US claimed
EP-2978747-B1 BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS SANOFI SA (FR) 2017-04-19 EP disclosed