SCHEMBL16109147

SCHEMBL16109147

COc1ccc(C(C)(C)C)cc1-c1cccc(C(CC(=O)O)c2nccs2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CTSA P10619 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18813178 1.00 CTSA (1.00) CTSA
SCHEMBL16109146 1.00 CTSA (1.00) CTSA
SCHEMBL18813430 0.92 CTSA (1.00) CTSA
SCHEMBL18813224 0.88 CTSA (1.00) CTSA
SCHEMBL18813366 0.88 CTSA (1.00) CTSA
SCHEMBL18813219 0.88 CTSA (1.00) CTSA
SCHEMBL18813250 0.87 CTSA (1.00) CTSA
SCHEMBL18813320 0.87 CTSA (1.00) CTSA
SCHEMBL18813252 0.87 CTSA (1.00) CTSA
SCHEMBL18813337 0.86 CTSA (1.00) CTSA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2978754-B1 BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS SANOFI SA (FR) 2017-05-10 EP claimed
EP-2978754-A1 BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS SANOFI (FR) 2016-02-03 EP claimed
US-9150526-B2 Biaryl-propionic acid derivatives and their use as pharmaceuticals SANOFI (FR) 2015-10-06 US claimed
US-20140296296-A1 Biaryl-Propionic Acid Derivatives and their Use as Pharmaceuticals SANOFI (FR) 2014-10-02 US claimed
WO-2014154726-A1 BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS SANOFI (FR) 2014-10-02 WO claimed
EP-2978754-B1 BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS SANOFI SA (FR) 2017-05-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140296296-A1 Biaryl-Propionic Acid Derivatives and their Use as Pharmaceuticals CTSV, F2R, CTSF CTSA 22/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.