Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CD69 | Q07108 | 1/20 | 0.32 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17285152 | 0.88 | CA9 (0.39) | CA9CA12CA2CA1TSHR | |
| SCHEMBL29904557 | 0.88 | CA9 (0.39) | CA9CA12CA2CA1TSHR | |
| SCHEMBL34470432 | 0.88 | CA9 (0.39) | CA9CA12CA2CA1TSHR | |
| SCHEMBL9796069 | 0.88 | CA9 (0.39) | CA9CA12CA2CA1TSHR | |
| SCHEMBL9796074 | 0.88 | CA9 (0.39) | CA9CA12CA2CA1TSHR | |
| SCHEMBL30560640 | 0.88 | CA9 (0.39) | CA9CA12CA2CA1TSHR | |
| SCHEMBL15975969 | 0.88 | CA9 (0.39) | CA9CA12CA2CA1TSHR | |
| SCHEMBL11249103 | 0.88 | CA9 (0.49) | CA9CA12CA2CA1TSHR | |
| SCHEMBL23133262 | 0.86 | CA9 (0.51) | CA9CA12CA2CA1TSHR | |
| SCHEMBL15596615 | 0.86 | CA9 (0.51) | CA9CA12CA2CA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150337259-A1 | METHODS AND COMPOSITIONS FOR MAKING ANTIBODIES AND ANTIBODY DERIVATIVES WITH REDUCED CORE FUCOSYLATION | SEAGEN INC. | 2015-11-26 | — | — | US | disclosed |