SCHEMBL17285233

SCHEMBL17285233

CN1NC(c2ccccc2)N(C)C1c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
KDM4E B2RXH2 3/20 0.38
HPGD P15428 3/20 0.38
ALOX12 P18054 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
PKM P14618 1/20 0.38
RAB9A P51151 1/20 0.38
RECQL P46063 1/20 0.36
POLB P06746 1/20 0.35
MAPT P10636 2/20 0.34
GAA P10253 2/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 2/20 0.33
RGS12 O14924 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
ALOX15 P16050 1/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15142022 0.78 KDM4E (0.46) ALDH1A1KDM4EHPGDALOX12TDP1
SCHEMBL17461108 0.68 ALDH1A1 (0.38) ALDH1A1KDM4EHPGDALOX12TDP1
SCHEMBL15340880 0.67 RECQL (0.43) ALDH1A1RECQLPOLBMAPTGAA
SCHEMBL15604977 0.67 ALDH1A1 (0.41) ALDH1A1KDM4EHPGDALOX12TDP1
SCHEMBL17775526 0.67 ALDH1A1 (0.41) ALDH1A1KDM4EHPGDALOX12TDP1
SCHEMBL12112818 0.67 KDM4E (0.37) ALDH1A1KDM4EHPGDALOX12TDP1
SCHEMBL17153987 0.66 ATM (0.39) KDM4ERECQLPOLBGAATSHR
SCHEMBL18691187 0.66 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDALOX12TDP1
SCHEMBL1830962 0.64 RECQL (0.44) ALDH1A1KDM4EHPGDALOX12TDP1
SCHEMBL14994638 0.64 PDGFRB (0.41) ALDH1A1RECQLPOLBGAACHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015178732-A1 MULTI-COMPONENT HOST MATERIAL AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2015-11-26 WO disclosed