Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.48 |
| ▸ | FDPS | P14324 | 2/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10695837 | 1.00 | SMPD1 (0.48) | SMPD1FDPSDNM1TSHRTHRB | |
| Bromide SCHEMBL19329912 | 1.00 | SMPD1 (0.48) | SMPD1FDPSDNM1TSHRTHRB | |
| Bromide SCHEMBL1967597 | 1.00 | SMPD1 (0.48) | SMPD1FDPSDNM1TSHRTHRB | |
| Bromide SCHEMBL6257335 | 1.00 | SMPD1 (0.48) | SMPD1FDPSDNM1TSHRTHRB | |
| Bromide SCHEMBL10697234 | 1.00 | SMPD1 (0.48) | SMPD1FDPSDNM1TSHRTHRB | |
| Bromide SCHEMBL10693787 | 1.00 | SMPD1 (0.48) | SMPD1FDPSDNM1TSHRTHRB | |
| Bromide SCHEMBL5088567 | 1.00 | SMPD1 (0.48) | SMPD1FDPSDNM1TSHRTHRB | |
| Bromide SCHEMBL10696126 | 1.00 | SMPD1 (0.48) | SMPD1FDPSDNM1TSHRTHRB | |
| Bromide SCHEMBL6258453 | 1.00 | SMPD1 (0.48) | SMPD1FDPSDNM1TSHRTHRB | |
| Bromide SCHEMBL335687 | 1.00 | SMPD1 (0.48) | SMPD1FDPSDNM1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113185705-B | Organic-inorganic hybrid material for single molecule detection and preparation method thereof | 深圳市光与生物科技有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-113185705-A | Organic-inorganic hybrid material for single molecule detection and preparation method thereof | 深圳市光与生物科技有限公司 | 2021-07-30 | — | — | CN | claimed |
| CN-114874709-A | Polyurethane protective film with low film tearing voltage | 惠州市浩明科技股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-113185705-B | Organic-inorganic hybrid material for single molecule detection and preparation method thereof | 深圳市光与生物科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-113185705-A | Organic-inorganic hybrid material for single molecule detection and preparation method thereof | 深圳市光与生物科技有限公司 | 2021-07-30 | — | — | CN | disclosed |
| US-10422792-B2 | Binding detection using liquid crystal | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2019-09-24 | — | — | US | disclosed |
| US-20170131266-A1 | Binding Detection Using Liquid Crystal | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2017-05-11 | — | — | US | disclosed |
| US-9631045-B2 | Polycarbodiimides having onium salt groups | PPG INDUSTRIES OHIO, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| EP-1457836-B2 | Developing solution for lithographic printing plate precursor and method for preparing lithographic printing plate | FUJIFILM CORP (JP) | 2016-08-17 | — | — | EP | disclosed |
| EP-1566700-B1 | Automatic development method of photosensitive lithographic printing plate and automatic development device thereof | FUJIFILM CORP (JP) | 2016-08-03 | — | — | EP | disclosed |
| EP-2354854-B2 | Method of making lithographic printing plate | FUJIFILM CORP (JP) | 2016-04-06 | — | — | EP | disclosed |
| EP-1400856-A2 | Method of making lithographic printing plate | FUJI PHOTO FILM CO., LTD. (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-20040053168-A1 | Exposing the heat-sensitive plate to light, and developing with an alkaline solution comprising sulfactants and salts; improve image contrast, resist to scratch, dispersing the development sludge | FUJI PHOTO FILM CO., LTD. | 2004-03-18 | — | — | US | disclosed |
| EP-1398151-A2 | Method of making lithographic printing plate | Fuji Photo Film Co., Ltd. (JP) | 2004-03-17 | — | — | EP | disclosed |
| EP-1378348-A2 | Thermosensitive lithographic printing plate | FUJI PHOTO FILM CO., LTD. (JP) | 2004-01-07 | — | — | EP | disclosed |
| US-20030108814-A1 | Recording layer contains an infrared ray absorbent, an alkali-soluble resin and a quaternary ammonium salt as inhibitor of inhibiting the alkali-soluble resin from dissolving in an alkali aqueous solution upon irridation | FUJI PHOTO FILM CO., LTD. | 2003-06-12 | — | — | US | disclosed |
| EP-1270218-A2 | Lithographic printing plate precursor and production method of lithographic printing plate | FUJI PHOTO FILM CO., LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| EP-1262318-A2 | Lithographic printing plate precursor | Fuji Photo Film Co., Ltd. (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-4289809-A | DEACTIVATION FOR BETTER SEPARATION OF POLAR COMPOUNDS | SCM CORPORATION (US) | 1981-09-15 | — | — | US | disclosed |
| US-4209554-A | PHOSPHONIUM SALTS | SCM CORPORATION (US) | 1980-06-24 | — | — | US | disclosed |