Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.48 |
| ▸ | FDPS | P14324 | 2/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10695837 | 1.00 | SMPD1 (0.48) | SMPD1FDPSDNM1TSHRTHRB | |
| Bromide SCHEMBL19329912 | 1.00 | SMPD1 (0.48) | SMPD1FDPSDNM1TSHRTHRB | |
| Bromide SCHEMBL1967597 | 1.00 | SMPD1 (0.48) | SMPD1FDPSDNM1TSHRTHRB | |
| Bromide SCHEMBL6257335 | 1.00 | SMPD1 (0.48) | SMPD1FDPSDNM1TSHRTHRB | |
| Bromide SCHEMBL10697234 | 1.00 | SMPD1 (0.48) | SMPD1FDPSDNM1TSHRTHRB | |
| Bromide SCHEMBL1728546 | 1.00 | SMPD1 (0.48) | SMPD1FDPSDNM1TSHRTHRB | |
| Bromide SCHEMBL10693787 | 1.00 | SMPD1 (0.48) | SMPD1FDPSDNM1TSHRTHRB | |
| Bromide SCHEMBL5088567 | 1.00 | SMPD1 (0.48) | SMPD1FDPSDNM1TSHRTHRB | |
| Bromide SCHEMBL10696126 | 1.00 | SMPD1 (0.48) | SMPD1FDPSDNM1TSHRTHRB | |
| Bromide SCHEMBL6258453 | 1.00 | SMPD1 (0.48) | SMPD1FDPSDNM1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 502 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122006818-A | Absent phosphotungstic acid quaternary ammonium salt catalyst and preparation method and application thereof | 中国林业科学研究院林产化学工业研究所 | 2026-05-12 | — | — | CN | claimed |
| CN-119569537-A | Preparation method of propargyl alcohol | 山东京博农化科技股份有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-119481189-A | Cathode organic electrolyte with phenothiazine quaternary ammonium salt structure, and preparation method and application thereof | 常州大学 | 2025-02-18 | — | — | CN | claimed |
| CN-118572068-A | Negative electrode material, preparation method thereof and battery | 江苏正力新能电池技术股份有限公司 | 2024-08-30 | — | — | CN | claimed |
| CN-118507103-A | Low-temperature conductive paste with high tension and application thereof | 苏州星翰新材料科技有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-118234906-A | Method for preparing cellulose pulp | 因多公司 | 2024-06-21 | — | — | CN | claimed |
| EP-2916820-B1 | DELIVERY OF BIOLOGICALLY-ACTIVE AGENTS USING VOLATILE, HYDROPHOBIC SOLVENTS | ROCHAL TECH LLC (US) | 2023-10-11 | — | — | EP | claimed |
| CN-113501749-B | Preparation method of multifunctional air-drying agent | 浙江皇马科技股份有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-114524718-B | Method for preparing high-purity phthalic dicarboxaldehyde from phthalic diester | 上海巽田科技股份有限公司 | 2023-09-22 | — | — | CN | claimed |
| CN-114436873-B | Preparation method of tranexamic acid | 上海巽田科技股份有限公司 | 2023-08-22 | — | — | CN | claimed |
| EP-0962434-B1 | Process for the preparation of aromatic olefins using palladium catalysts containing phosphite ligands | DEGUSSA (DE) | 2002-11-27 | — | — | EP | claimed |
| US-20020107426-A1 | Process for the preparation of mono-, bi- or poly- functional biaryls | UMICORE AG & CO. KG (DE) | 2002-08-08 | — | — | US | claimed |
| EP-0453993-B1 | PROCESS FOR PRODUCING A HALOMETHYL PIVALATE | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 1993-07-07 | — | — | EP | claimed |
| US-5202462-A | Catalytic reaction of metal salt of pivalic acid with dihalomethane in presence of phase transfer catalyst | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-04-13 | — | — | US | claimed |
| EP-0453993-A1 | Process for producing a halomethyl pivalate | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 1991-10-30 | — | — | EP | claimed |
| EP-0268261-A1 | Process for producing 1-hydrocarbyl mercaptans | PHILLIPS PETROLEUM COMPANY (US) | 1988-05-25 | — | — | EP | claimed |
| US-4514571-A | Process for the preparation of urea derivatives | UBE INDUSTRIES, LTD. (JP) | 1985-04-30 | — | — | US | claimed |
| EP-0071576-B1 | PROCESS FOR THE PREPARATION OF 1-AMINO-4-HYDROXY ANTHRAQUINONES | CIBA-GEIGY AG (CH) | 1985-01-23 | — | — | EP | claimed |
| US-4485043-A | Process for producing 1-amino-4-hydroxy-anthraquinones | CIBA-GEIGY AG (CH) | 1984-11-27 | — | — | US | claimed |
| US-4182882-A | Process for the production of pyranthrones or flavanthrones | CIBA-GEIGY CORPORATION (US) | 1980-01-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107426-A1 | Process for the preparation of mono-, bi- or poly- functional biaryls | CYP4F3, CYP4F2, CYP2F1 | SMPD1 4318/4885FDPS 192/4885DNM1 2019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.