Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM2 | Q9P1W9 | 20/20 | 0.43 |
| ▸ | PIM1 | P11309 | 19/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 19/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17282382 | 0.92 | PIM2 (0.44) | PIM2PIM1PIM3 | |
| SCHEMBL17286146 | 0.87 | PIM2 (0.45) | PIM2PIM1PIM3 | |
| SCHEMBL15588962 | 0.85 | PIM2 (0.47) | PIM2PIM1PIM3 | |
| SCHEMBL15547790 | 0.84 | EIF2AK4 (0.34) | PIM2PIM1PIM3 | |
| SCHEMBL15534941 | 0.83 | PIM2 (0.38) | PIM2PIM1PIM3 | |
| Isobutane SCHEMBL15547791 | 0.83 | PIM2 (0.36) | PIM2PIM1PIM3 | |
| SCHEMBL15887134 | 0.82 | PIM1 (0.39) | PIM2PIM1PIM3 | |
| SCHEMBL17282381 | 0.82 | PIM2 (0.49) | PIM2PIM1PIM3 | |
| SCHEMBL16587832 | 0.80 | PIM2 (0.51) | PIM2PIM1PIM3 | |
| SCHEMBL15534438 | 0.79 | PIM2 (0.46) | PIM2PIM1PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150336960-A1 | ARYL-SUBSTITUTED FUSED BICYCLIC PYRIDAZINE COMPOUNDS | NOVARTIS AG (CH) | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336960-A1 | ARYL-SUBSTITUTED FUSED BICYCLIC PYRIDAZINE COMPOUNDS | PIM1, PIM2, PIM3 | PIM2 2/4885PIM1 1/4885PIM3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.