Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.51 |
| ▸ | APLNR | P35414 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.50 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 4/20 | 0.47 |
| ▸ | CALCR | P30988 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | GLP1R | P43220 | 1/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.46 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.46 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.46 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSH | P09668 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17274190 | 1.00 | C5AR1 (0.51) | C5AR1APLNRAGTR1EPHA2AGTR2 | |
| SCHEMBL19780604 | 0.97 | C5AR1 (0.52) | C5AR1APLNRAGTR1EPHA2AGTR2 | |
| SCHEMBL19780600 | 0.97 | C5AR1 (0.52) | C5AR1APLNRAGTR1EPHA2AGTR2 | |
| SCHEMBL17287131 | 0.96 | AGTR1 (0.51) | C5AR1APLNRAGTR1EPHA2AGTR2 | |
| SCHEMBL17274223 | 0.94 | AGTR1 (0.49) | C5AR1APLNRAGTR1AGTR2F2 | |
| SCHEMBL17274210 | 0.94 | AGTR1 (0.49) | C5AR1APLNRAGTR1AGTR2F2 | |
| SCHEMBL17287128 | 0.94 | AGTR1 (0.49) | C5AR1APLNRAGTR1AGTR2F2 | |
| SCHEMBL18699989 | 0.90 | AGTR1 (0.51) | C5AR1AGTR1AGTR2F2CALCR | |
| SCHEMBL18699890 | 0.90 | C5AR1 (0.49) | C5AR1APLNRAGTR1EPHA2AGTR2 | |
| SCHEMBL17274224 | 0.90 | C5AR1 (0.46) | C5AR1APLNRAGTR1EPHA2AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015179349-A2 | SYNTHESIS OF BETA-ARRESTIN EFFECTORS | TREVENA, INC. (US) | 2015-11-26 | — | — | WO | disclosed |