Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM10 | O14672 | 20/20 | 0.77 |
| ▸ | MMP2 | P08253 | 18/20 | 0.77 |
| ▸ | MMP9 | P14780 | 10/20 | 0.77 |
| ▸ | MMP3 | P08254 | 7/20 | 0.77 |
| ▸ | ERBB2 | P04626 | 15/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17288039 | 1.00 | ADAM10 (0.77) | ADAM10MMP2MMP9MMP3ERBB2 | |
| SCHEMBL16500294 | 0.88 | ADAM10 (0.74) | ADAM10MMP2MMP9MMP3ERBB2 | |
| SCHEMBL1364254 | 0.87 | ADAM10 (1.00) | ADAM10MMP2MMP9MMP3ERBB2 | |
| SCHEMBL1364454 | 0.87 | ADAM10 (1.00) | ADAM10MMP2MMP9MMP3ERBB2 | |
| SCHEMBL17288043 | 0.84 | ADAM10 (0.69) | ADAM10MMP2MMP9MMP3ERBB2 | |
| SCHEMBL17288031 | 0.84 | ADAM10 (0.62) | ADAM10MMP2MMP9MMP3ERBB2 | |
| SCHEMBL1364040 | 0.83 | ADAM10 (0.92) | ADAM10MMP2MMP9MMP3ERBB2 | |
| SCHEMBL1364039 | 0.83 | ADAM10 (0.92) | ADAM10MMP2MMP9MMP3ERBB2 | |
| SCHEMBL1366512 | 0.83 | ADAM10 (0.92) | ADAM10MMP2MMP9MMP3ERBB2 | |
| SCHEMBL1364060 | 0.83 | ADAM10 (0.92) | ADAM10MMP2MMP9MMP3ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622569-B1 | AZA SPIRO ALKANE DERIVATIVES AS INHIBITORS OF METALLPROTEASES | INCYTE CORP (US) | 2015-12-02 | — | — | EP | claimed |