SCHEMBL17288356

SCHEMBL17288356

COc1cccc(CCc2cc(C(=O)O)no2)c1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
HPGD P15428 2/20 0.56
POLB P06746 1/20 0.53
MEN1 O00255 1/20 0.48
LMNA P02545 1/20 0.48
KMT2A Q03164 1/20 0.48
AKR1C3 P42330 1/20 0.47
NR3C2 P08235 1/20 0.47
MTNR1A P48039 2/20 0.47
MTNR1B P49286 2/20 0.47
MAPT P10636 1/20 0.47
RECQL P46063 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
CYP1A2 P05177 1/20 0.46
HDAC1 Q13547 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11099405 0.88 ALDH1A1 (0.58) ALDH1A1HPGDPOLBMEN1LMNA
Hydrochloric Acid SCHEMBL11100107 0.87 ALDH1A1 (0.56) ALDH1A1HPGDPOLBMEN1LMNA
SCHEMBL15931931 0.85 ALDH1A1 (0.54) ALDH1A1HPGDPOLBMEN1LMNA
SCHEMBL17289096 0.84 DAO (0.46) POLB
SCHEMBL17288546 0.82 SMN1; SMN2 (0.47) ALDH1A1POLBKMT2AAKR1C3NR3C2
SCHEMBL8283554 0.81 SMN1; SMN2 (0.56) ALDH1A1POLBNPC1RAB9AHDAC1
SCHEMBL17309743 0.80 HCAR2 (0.49) POLBNR3C2TAAR1NPC1RAB9A
SCHEMBL15931855 0.79 MAPT (0.51) ALDH1A1HPGDPOLBLMNAAKR1C3
SCHEMBL4257586 0.78 AKR1C3 (0.49) ALDH1A1POLBKMT2AAKR1C3NR3C2
SCHEMBL5451857 0.77 ALDH1A1 (0.55) ALDH1A1HPGDLMNAKMT2AMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 ALDH1A1 3053/4885HPGD 1605/4885POLB 4377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.