SCHEMBL17288609

SCHEMBL17288609

C#Cc1ccc2c([C](F)F)cccc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 2/20 0.43
CYP1B1 Q16678 2/20 0.43
PARP1 P09874 1/20 0.40
PTPN1 P18031 2/20 0.38
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
CYP1A2 P05177 1/20 0.34
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA12 O43570 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
NR4A1 P22736 1/20 0.32
NR4A2 P43354 1/20 0.32
NR4A3 Q92570 1/20 0.32
FFAR1 O14842 1/20 0.31
AURKA O14965 1/20 0.30
RPS6KB1 P23443 1/20 0.30
PLAU P00749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17288524 0.83 CA1 (0.49) PARP1PTPN1CA1CA2
SCHEMBL689994 0.81 PTPN1 (0.60) CYP1A1CYP1B1PARP1PTPN1KDM4E
SCHEMBL17288783 0.81 CYP1A1 (0.40) CYP1A1CYP1B1PTPN1KDM4EALDH1A1
SCHEMBL7138077 0.76 CYP1A1 (0.50) CYP1A1CYP1B1PARP1ALDH1A1CYP1A2
SCHEMBL17288414 0.74 CYP1A2 (0.45) PTPN1KDM4EALDH1A1GAACYP1A2
SCHEMBL17288481 0.74 TLR8 (0.46) PTPN1GAACYP1A2
SCHEMBL16288874 0.73 CYP1A1 (0.47) CYP1A1CYP1B1PARP1PTPN1CYP1A2
SCHEMBL16288876 0.73 CYP1A2 (0.57) CYP1A1CYP1B1ALDH1A1CYP1A2CA1
SCHEMBL17288463 0.73 CYP2A6 (0.43) PTPN1KDM4EALDH1A1GAANR4A1
SCHEMBL692894 0.73 ALDH1A1 (0.48) CYP1A1CYP1B1PARP1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 CYP1A1 117/4885CYP1B1 331/4885PARP1 4545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.