Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.54 |
| ▸ | AHR | P35869 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836819 | 0.86 | MAOA (0.61) | MAOAMEN1KMT2APOLBCTDSP1 | |
| SCHEMBL13672151 | 0.86 | KDM4E (0.50) | AHRMEN1KMT2APOLBCTDSP1 | |
| SCHEMBL172820 | 0.84 | MAOA (0.61) | MAOAAHRMEN1KMT2ACYP1A2 | |
| SCHEMBL3874960 | 0.84 | AHR (0.59) | MAOAAHRMEN1KMT2AHPGD | |
| SCHEMBL24311391 | 0.81 | MAOA (0.57) | MAOAAHRMEN1KMT2ACYP1A2 | |
| SCHEMBL26768129 | 0.80 | KDM4E (0.54) | MAOAMEN1KMT2APOLBCTDSP1 | |
| SCHEMBL26767072 | 0.80 | KDM4E (0.54) | MAOAMEN1KMT2APOLBCTDSP1 | |
| SCHEMBL9837713 | 0.80 | MAOA (0.61) | MAOAMEN1KMT2AHPGDMAPT | |
| SCHEMBL31145593 | 0.79 | AHR (0.49) | MAOAAHRMEN1KMT2ACYP1A2 | |
| SCHEMBL31192626 | 0.78 | AHR (0.52) | MAOAAHRMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021126729-A1 | PRMT5 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2021-06-24 | — | — | WO | disclosed |
| EP-1521125-B1 | Electrophotographic photoconductor, electrophotographic method, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound | RICOH CO LTD (JP) | 2012-03-07 | — | — | EP | disclosed |