Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 10/20 | 0.55 |
| ▸ | SKP1 | P63208 | 10/20 | 0.55 |
| ▸ | SKP2 | Q13309 | 10/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14796957 | 0.93 | CKS1B (0.48) | CKS1BSKP1SKP2CHRM4GRIN2B | |
| SCHEMBL1728812 | 0.91 | CKS1B (0.56) | CKS1BSKP1SKP2CETP | |
| SCHEMBL1711018 | 0.89 | CHRM4 (0.57) | CKS1BSKP1SKP2CHRM4HTR1A | |
| SCHEMBL16174433 | 0.84 | GRM1 (0.43) | CKS1BSKP1SKP2GRIN2BHTR1A | |
| SCHEMBL16174434 | 0.84 | GRM1 (0.43) | CKS1BSKP1SKP2GRIN2BHTR1A | |
| SCHEMBL3269094 | 0.83 | CKS1B (0.47) | CKS1BSKP1SKP2CHRM4GRIN2B | |
| SCHEMBL1729788 | 0.82 | TDO2 (0.53) | CKS1BSKP1SKP2GRIN2BHTR1A | |
| SCHEMBL3723104 | 0.82 | GRIN2B (0.40) | CKS1BSKP1SKP2GRIN2BHTR1A | |
| SCHEMBL1729621 | 0.82 | CKS1B (0.51) | CKS1BSKP1SKP2 | |
| SCHEMBL1727740 | 0.81 | CKS1B (0.47) | CKS1BSKP1SKP2CHRM4CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |