Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.60 |
| ▸ | PPARD | Q03181 | 6/20 | 0.60 |
| ▸ | PPARA | Q07869 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 9/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268946 | 0.85 | PPARG (0.53) | PPARGPPARDPPARANPC1RAB9A | |
| SCHEMBL1729622 | 0.85 | RAB9A (0.57) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL334455 | 0.83 | NPC1 (0.62) | PPARGPPARDPPARANPC1RAB9A | |
| SCHEMBL335645 | 0.82 | NPC1 (0.64) | PPARGPPARDPPARANPC1RAB9A | |
| SCHEMBL335795 | 0.81 | PPARD (0.72) | PPARGPPARDPPARANPC1SMN1; SMN2 | |
| SCHEMBL10219837 | 0.81 | NPC1 (0.65) | PPARGPPARDPPARANPC1RAB9A | |
| SCHEMBL10220809 | 0.81 | PPARD (0.71) | PPARGPPARDPPARANPC1MAPT | |
| SCHEMBL10219814 | 0.80 | NPC1 (0.67) | PPARGPPARDPPARANPC1RAB9A | |
| SCHEMBL333932 | 0.79 | NPC1 (0.61) | PPARGPPARDPPARANPC1RAB9A | |
| SCHEMBL346050 | 0.79 | HRH3 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |