SCHEMBL1729150

SCHEMBL1729150

CNC(=O)CN(C(=O)O)C1CCN(c2nccc3ccccc23)CC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 1/20 0.48
HTR2C P28335 1/20 0.48
HCAR2 Q8TDS4 1/20 0.46
MALT1 Q9UDY8 1/20 0.46
SORD Q00796 2/20 0.44
DPP4 P27487 1/20 0.42
DPP7 Q9UHL4 1/20 0.42
OPRL1 P41146 1/20 0.41
DRD2 P14416 2/20 0.40
DRD3 P35462 1/20 0.40
DRD4 P21917 1/20 0.40
ACACB O00763 1/20 0.40
PHGDH O43175 1/20 0.40
RPLP1 P05386 1/20 0.38
RPLP0 P05388 1/20 0.38
RPS17 P08708 1/20 0.38
RPSA P08865 1/20 0.38
RPS2 P15880 1/20 0.38
RPL35A P18077 1/20 0.38
RPL7 P18124 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL239313 0.87 HRH4 (0.46) HRH4HTR2CHCAR2MALT1SORD
Hydrochloric Acid SCHEMBL239760 0.86 HRH4 (0.45) HRH4HTR2CHCAR2MALT1SORD
SCHEMBL1727927 0.85 HRH4 (0.44) HRH4HTR2CHCAR2MALT1SORD
SCHEMBL1728700 0.82 HRH4 (0.54) HRH4HTR2CHCAR2MALT1SORD
SCHEMBL239312 0.78 HRH4 (0.45) HRH4HTR2CHCAR2MALT1SORD
Hydrochloric Acid SCHEMBL239759 0.77 HRH4 (0.44) HRH4HTR2CHCAR2MALT1SORD
SCHEMBL3265696 0.76 MALT1 (0.46) HRH4HTR2CHCAR2MALT1SORD
SCHEMBL3265718 0.76 MALT1 (0.45) HRH4HTR2CHCAR2MALT1SORD
SCHEMBL1728699 0.75 HRH4 (0.51) HRH4HTR2CHCAR2MALT1SORD
SCHEMBL4582824 0.74 HCAR2 (0.48) HRH4HTR2CHCAR2MALT1SORD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1633735-B1 DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS SANOFI SA (FR) 2011-11-30 EP claimed