Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.48 |
| ▸ | SORD | Q00796 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729150 | 0.82 | HRH4 (0.48) | HRH4HTR2CHCAR2MALT1SORD | |
| SCHEMBL18980472 | 0.78 | ADRB2 (0.51) | DPP4DRD2DRD3KMT2A | |
| SCHEMBL4582824 | 0.78 | HCAR2 (0.48) | HRH4HTR2CHCAR2MALT1SORD | |
| SCHEMBL1267034 | 0.77 | MEN1 (0.52) | KMT2A | |
| SCHEMBL2123974 | 0.77 | MEN1 (0.48) | KMT2A | |
| SCHEMBL27902619 | 0.76 | ACACB (0.46) | HRH4SORDACACB | |
| SCHEMBL1728699 | 0.76 | HRH4 (0.51) | HRH4HTR2CHCAR2MALT1SORD | |
| SCHEMBL239313 | 0.75 | HRH4 (0.46) | HRH4HTR2CHCAR2MALT1SORD | |
| SCHEMBL237050 | 0.75 | HTR2C (0.64) | HRH4HTR2CSORD | |
| SCHEMBL4015416 | 0.74 | HRH4 (0.63) | HRH4HTR2CHCAR2MALT1SORD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | disclosed |
| EP-1633735-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004099176-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2004-11-18 | — | — | WO | disclosed |