Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | SPR | P35270 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17134855 | 0.93 | DRD4 (0.41) | DRD4DRD2DRD3RAB9ANPC1 | |
| SCHEMBL17135011 | 0.91 | SPR (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17134973 | 0.86 | DRD4 (0.41) | DRD4DRD2DRD3RAB9ANPC1 | |
| SCHEMBL17134702 | 0.84 | KMT2A (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17134622 | 0.84 | CNR2 (0.40) | SPRCCKBREGLN1NPC1KMT2A | |
| SCHEMBL17134905 | 0.84 | POLB (0.42) | DRD4DRD2DRD3RAB9AKMT2A | |
| SCHEMBL17135019 | 0.83 | CNR2 (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17134661 | 0.83 | PARP14 (0.38) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17134922 | 0.82 | CA12 (0.39) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17134854 | 0.82 | MAPT (0.48) | RAB9ANPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182734-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | 協和発酵キリン株式会社 | 2015-12-03 | — | — | WO | disclosed |