Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 15/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5488911 | 0.99 | F2R (0.52) | F2RMEN1KMT2AKDM4ENPC1 | |
| Bromide SCHEMBL1731721 | 0.88 | F2R (0.52) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1731641 | 0.87 | F2R (0.50) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL14449151 | 0.87 | F2R (0.59) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1730396 | 0.86 | F2R (0.60) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1729420 | 0.85 | F2R (0.70) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1731526 | 0.85 | F2R (0.61) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL14449120 | 0.84 | F2R (0.53) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1729929 | 0.84 | F2R (0.47) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1728702 | 0.84 | F2R (0.54) | F2RKDM4ENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |