SCHEMBL17293539

SCHEMBL17293539

Cn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(Br)cc1Br

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
IL15 P40933 20/20 1.00
IL15RA Q13261 20/20 1.00
IL2 P60568 4/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17293542 0.87 IL15 (1.00) IL15IL15RAIL2
SCHEMBL17293831 0.87 IL15 (1.00) IL15IL15RAIL2
SCHEMBL17293792 0.86 IL15 (1.00) IL15IL15RAIL2
SCHEMBL17293753 0.86 IL15 (1.00) IL15IL15RAIL2
SCHEMBL17293642 0.86 IL15 (1.00) IL15IL15RAIL2
SCHEMBL17293839 0.86 IL15 (1.00) IL15IL15RAIL2
SCHEMBL17293574 0.86 IL15 (1.00) IL15IL15RAIL2
SCHEMBL17293662 0.86 IL15 (1.00) IL15IL15RAIL2
SCHEMBL17293815 0.86 IL15 (1.00) IL15IL15RAIL2
SCHEMBL17293788 0.84 IL15 (1.00) IL15IL15RAIL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015181394-A1 NOVEL IL-2/IL-15 RECEPTOR ANTAGONIST COMPOUNDS AND USES THEREOF FOR THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASES OR GRAFT REJECTION INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2015-12-03 WO claimed
WO-2015181394-A1 NOVEL IL-2/IL-15 RECEPTOR ANTAGONIST COMPOUNDS AND USES THEREOF FOR THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASES OR GRAFT REJECTION INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2015-12-03 WO disclosed