Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 8/20 | 0.51 |
| ▸ | SKP1 | P63208 | 8/20 | 0.51 |
| ▸ | SKP2 | Q13309 | 8/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729621 | 0.86 | CKS1B (0.51) | CKS1BSKP1SKP2HRH3ALDH1A1 | |
| SCHEMBL19598739 | 0.83 | HRH3 (0.54) | HRH3ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3266247 | 0.82 | HRH3 (0.46) | CKS1BSKP1SKP2HRH3ALDH1A1 | |
| SCHEMBL1727740 | 0.82 | CKS1B (0.47) | CKS1BSKP1SKP2ALDH1A1RAB9A | |
| SCHEMBL1727907 | 0.82 | DEGS1 (0.56) | CKS1BSKP1SKP2MAPTKDM4E | |
| SCHEMBL19598748 | 0.81 | HRH3 (0.52) | HRH3ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL1728812 | 0.81 | CKS1B (0.56) | CKS1BSKP1SKP2CETP | |
| SCHEMBL10044278 | 0.80 | HRH3 (0.51) | HRH3ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL1729285 | 0.80 | CHRM4 (0.57) | CETP | |
| SCHEMBL1728740 | 0.80 | LMNA (0.61) | CKS1BSKP1SKP2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |