SCHEMBL17294763

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17294624	1.00	TSHR (0.50)	TSHRCCR1SSTR4P2RX4CHRM3
	SCHEMBL17294744	1.00	TSHR (0.50)	TSHRCCR1SSTR4P2RX4CHRM3
	SCHEMBL17294636	0.83	HTT (0.50)	TSHRCCR1CHRM3GAANPSR1
	SCHEMBL17294696	0.83	HTT (0.50)	TSHRCCR1CHRM3GAANPSR1
	SCHEMBL17294637	0.83	HTT (0.50)	TSHRCCR1CHRM3GAANPSR1
	SCHEMBL17294635	0.83	HTT (0.50)	TSHRCCR1CHRM3GAANPSR1
	SCHEMBL17294773	0.83	HTT (0.50)	TSHRCCR1CHRM3GAANPSR1
	SCHEMBL17294771	0.83	HTT (0.50)	TSHRCCR1CHRM3GAANPSR1
	SCHEMBL17294633	0.83	HTT (0.50)	TSHRCCR1CHRM3GAANPSR1
	SCHEMBL4620504	0.83	TSHR (0.60)	TSHRKDM4EGAANPSR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.