Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 6/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5483132 | 0.99 | F2R (0.51) | F2ROPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL27506514 | 0.92 | F2R (0.50) | F2RKDM4ETSHRALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL1729405 | 0.91 | F2R (0.51) | F2RKDM4ETSHRALDH1A1GAA | |
| SCHEMBL6544914 | 0.80 | F2R (0.54) | F2RKDM4ELMNATSHRALDH1A1 | |
| Bromide SCHEMBL1732738 | 0.80 | F2R (0.60) | F2RKDM4EALDH1A1GAAMAPT | |
| Bromide SCHEMBL1729181 | 0.79 | KDM4E (0.37) | F2ROPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL28740926 | 0.78 | F2R (0.56) | F2RKDM4ETSHRALDH1A1GAA | |
| Bromide SCHEMBL1731325 | 0.78 | F2R (0.56) | F2RKDM4ETSHRALDH1A1GAA | |
| SCHEMBL27507748 | 0.77 | F2R (0.51) | F2RKDM4EALDH1A1GAAMAPT | |
| SCHEMBL1729167 | 0.77 | F2R (0.56) | F2RKDM4ELMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |