Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 12/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 12/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17295265 | 1.00 | S1PR1 (0.47) | S1PR1S1PR3CFTRCA9DYRK2 | |
| SCHEMBL19096377 | 0.96 | S1PR1 (0.45) | S1PR1S1PR3CFTRCA9DYRK2 | |
| SCHEMBL19096625 | 0.95 | CFTR (0.47) | S1PR1S1PR3CFTRCA9DYRK2 | |
| SCHEMBL17302125 | 0.93 | S1PR1 (0.51) | S1PR1S1PR3CFTRCA9DYRK2 | |
| SCHEMBL19096607 | 0.91 | MGAM (0.46) | S1PR1S1PR3CFTRCA9DYRK2 | |
| SCHEMBL19096247 | 0.91 | MGAM (0.46) | S1PR1S1PR3CFTRDYRK2PIM1 | |
| SCHEMBL19096567 | 0.89 | FAAH (0.49) | S1PR1S1PR3CFTRDYRK2PIM1 | |
| SCHEMBL19096576 | 0.89 | S1PR1 (0.55) | S1PR1S1PR3CFTRALDH1A1MAPT | |
| SCHEMBL19096569 | 0.86 | MEN1 (0.54) | S1PR1S1PR3CA9ALDH1A1MAPT | |
| SCHEMBL19096404 | 0.85 | S1PR1 (0.52) | S1PR1S1PR3CFTRCA9DYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148990-A1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | Universität Bern (CH) | 2017-04-05 | — | — | EP | disclosed |
| WO-2015181337-A1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | Universität Bern (CH) | 2015-12-03 | — | — | WO | disclosed |