Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | FNTA | P49354 | 2/20 | 0.32 |
| ▸ | FNTB | P49356 | 2/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17295311 | 0.92 | NSD2 (0.37) | NSD2EP300EGLN1FNTAFNTB | |
| SCHEMBL17295546 | 0.89 | FNTA (0.43) | FNTAFNTBPGGT1B | |
| SCHEMBL17301899 | 0.83 | CYP19A1 (0.35) | NSD2FNTAFNTBPGGT1BCYP19A1 | |
| SCHEMBL17295256 | 0.80 | FNTA (0.48) | FNTAFNTBPGGT1B | |
| SCHEMBL17295175 | 0.79 | LTB4R2 (0.42) | LPAR1FNTAFNTBPGGT1B | |
| SCHEMBL17295282 | 0.79 | FNTA (0.39) | FNTAFNTBPGGT1B | |
| SCHEMBL17295221 | 0.78 | FNTA (0.40) | FNTAFNTBPGGT1B | |
| SCHEMBL17295284 | 0.76 | FNTA (0.41) | FNTAFNTBPGGT1B | |
| SCHEMBL17295383 | 0.76 | FNTA (0.47) | FNTAFNTBPGGT1B | |
| SCHEMBL17295387 | 0.75 | FNTA (0.42) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015181272-A1 | RAB GERANYLGERANYL TRANSFERASE INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2015-12-03 | — | — | WO | disclosed |
| WO-2015181272-A1 | RAB GERANYLGERANYL TRANSFERASE INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2015-12-03 | — | — | WO | disclosed |