Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.35 |
| ▸ | NSD2 | O96028 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
| ▸ | ICMT | O60725 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17302044 | 0.91 | CYP19A1 (0.38) | CYP19A1NSD2FNTAFNTBPGGT1B | |
| SCHEMBL17302059 | 0.86 | FNTA (0.43) | FNTAFNTBPGGT1B | |
| SCHEMBL17295273 | 0.83 | NSD2 (0.34) | CYP19A1NSD2FNTAFNTBPGGT1B | |
| SCHEMBL17295329 | 0.76 | FNTA (0.49) | FNTAFNTBPGGT1B | |
| SCHEMBL17295548 | 0.75 | CYP19A1 (0.42) | CYP19A1FNTAFNTBPGGT1B | |
| SCHEMBL17301909 | 0.75 | FNTA (0.38) | FNTAFNTBPGGT1B | |
| SCHEMBL17295311 | 0.74 | NSD2 (0.37) | CYP19A1NSD2FNTAFNTBPGGT1B | |
| SCHEMBL17301918 | 0.74 | FNTA (0.39) | FNTAFNTBPGGT1B | |
| SCHEMBL17295308 | 0.71 | FNTA (0.48) | FNTAFNTBPGGT1B | |
| SCHEMBL17295546 | 0.71 | FNTA (0.43) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015181272-A1 | RAB GERANYLGERANYL TRANSFERASE INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2015-12-03 | — | — | WO | disclosed |