Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 18/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 18/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17295522 | 1.00 | S1PR3 (0.51) | S1PR3S1PR1MEN1ALDH1A1KMT2A | |
| SCHEMBL17295641 | 0.88 | S1PR1 (0.48) | S1PR3S1PR1MEN1ALDH1A1KMT2A | |
| SCHEMBL17295639 | 0.88 | S1PR1 (0.48) | S1PR3S1PR1MEN1ALDH1A1KMT2A | |
| SCHEMBL17295527 | 0.84 | S1PR1 (0.45) | S1PR3S1PR1MEN1ALDH1A1KMT2A | |
| SCHEMBL17295529 | 0.84 | S1PR1 (0.45) | S1PR3S1PR1MEN1ALDH1A1KMT2A | |
| SCHEMBL19096258 | 0.84 | S1PR3 (0.53) | S1PR3S1PR1 | |
| SCHEMBL17295264 | 0.83 | S1PR1 (0.50) | S1PR3S1PR1MEN1ALDH1A1KMT2A | |
| SCHEMBL17295263 | 0.83 | S1PR1 (0.50) | S1PR3S1PR1MEN1ALDH1A1KMT2A | |
| SCHEMBL17295518 | 0.83 | ALDH1A1 (0.49) | S1PR3S1PR1MEN1ALDH1A1KMT2A | |
| SCHEMBL17295520 | 0.83 | ALDH1A1 (0.49) | S1PR3S1PR1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148990-A1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | Universität Bern (CH) | 2017-04-05 | — | — | EP | disclosed |
| WO-2015181337-A1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | Universität Bern (CH) | 2015-12-03 | — | — | WO | disclosed |