Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 15/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 15/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17295640 | 1.00 | FAAH (0.45) | FAAHS1PR1S1PR3MEN1ALDH1A1 | |
| SCHEMBL20932949 | 0.89 | S1PR1 (0.50) | FAAHS1PR1S1PR3MEN1ALDH1A1 | |
| SCHEMBL17302224 | 0.89 | FAAH (0.54) | FAAHS1PR1S1PR3MEN1ALDH1A1 | |
| SCHEMBL17295493 | 0.86 | FAAH (0.45) | FAAHS1PR1S1PR3MEN1ALDH1A1 | |
| SCHEMBL17295495 | 0.86 | FAAH (0.45) | FAAHS1PR1S1PR3MEN1ALDH1A1 | |
| SCHEMBL17302139 | 0.85 | MEN1 (0.59) | FAAHS1PR1S1PR3MEN1ALDH1A1 | |
| SCHEMBL17302228 | 0.84 | S1PR1 (0.59) | FAAHS1PR1S1PR3 | |
| SCHEMBL17295356 | 0.84 | S1PR1 (0.58) | FAAHS1PR1S1PR3MEN1ALDH1A1 | |
| SCHEMBL17295355 | 0.84 | S1PR1 (0.58) | FAAHS1PR1S1PR3MEN1ALDH1A1 | |
| SCHEMBL17295458 | 0.84 | FAAH (0.59) | FAAHS1PR1S1PR3MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148990-A1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | Universität Bern (CH) | 2017-04-05 | — | — | EP | disclosed |
| WO-2015181337-A1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | Universität Bern (CH) | 2015-12-03 | — | — | WO | disclosed |