Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | FAAH | O00519 | 4/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17295644 | 1.00 | MEN1 (0.54) | MEN1KMT2AALDH1A1NPSR1FAAH | |
| SCHEMBL19096569 | 0.96 | MEN1 (0.54) | MEN1KMT2AALDH1A1NPSR1FAAH | |
| SCHEMBL19096526 | 0.95 | FAAH (0.58) | MEN1KMT2AALDH1A1NPSR1FAAH | |
| SCHEMBL17302145 | 0.93 | MEN1 (0.62) | MEN1KMT2AALDH1A1NPSR1FAAH | |
| SCHEMBL19096261 | 0.91 | FAAH (0.58) | MEN1KMT2AALDH1A1NPSR1FAAH | |
| SCHEMBL17295338 | 0.91 | FAAH (0.54) | MEN1KMT2AALDH1A1NPSR1FAAH | |
| SCHEMBL19096521 | 0.91 | FAAH (0.58) | MEN1KMT2AALDH1A1NPSR1FAAH | |
| SCHEMBL17295340 | 0.91 | FAAH (0.54) | MEN1KMT2AALDH1A1NPSR1FAAH | |
| SCHEMBL17295576 | 0.90 | FAAH (0.57) | MEN1KMT2AALDH1A1NPSR1FAAH | |
| SCHEMBL17295574 | 0.90 | FAAH (0.57) | MEN1KMT2AALDH1A1NPSR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148990-A1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | Universität Bern (CH) | 2017-04-05 | — | — | EP | disclosed |
| WO-2015181337-A1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | Universität Bern (CH) | 2015-12-03 | — | — | WO | disclosed |