Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 3/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21369533 | 0.87 | ESR2 (0.43) | HDAC1MEN1KMT2AGRM5GRM1 | |
| SCHEMBL5341383 | 0.87 | ESR2 (0.43) | HDAC1MEN1KMT2AGRM5GRM1 | |
| SCHEMBL5341385 | 0.87 | ESR2 (0.43) | HDAC1MEN1KMT2AGRM5GRM1 | |
| SCHEMBL26215454 | 0.86 | MAPT (0.50) | HDAC1ESR2RORC | |
| SCHEMBL4635083 | 0.86 | GRM5 (0.46) | HDAC1MEN1KMT2AHDAC2GRM5 | |
| SCHEMBL17542019 | 0.86 | HDAC1 (0.48) | HDAC1ESR2RORCNR1H2MAPK1 | |
| SCHEMBL17541997 | 0.86 | NR1H2 (0.50) | HDAC1MEN1KMT2AHDAC2ESR2 | |
| SCHEMBL16716828 | 0.85 | MAPK1 (0.48) | HDAC1MEN1KMT2AESR2RORC | |
| SCHEMBL12525814 | 0.83 | GPR119 (0.43) | HDAC1GRM5GRM1ESR2NR1H2 | |
| SCHEMBL21816667 | 0.82 | NR1H2 (0.46) | HDAC1MEN1KMT2ANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015181799-A1 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS | FOUNDATION FOR NEGLECTED DISEASE RESEARCH (IN) | 2015-12-03 | — | — | WO | disclosed |
| WO-2015181799-A1 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS | FOUNDATION FOR NEGLECTED DISEASE RESEARCH (IN) | 2015-12-03 | — | — | WO | disclosed |