Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 6/20 | 0.59 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLR1A | O95602 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | UHRF1 | Q96T88 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564929 | 0.93 | RAD52 (0.54) | RAD52SMARCA2MAPTCYP1A2CYP2C9 | |
| SCHEMBL7571923 | 0.93 | RAD52 (0.56) | RAD52SMARCA2MAPTCYP1A2CYP2C9 | |
| SCHEMBL7566375 | 0.87 | RAD52 (0.51) | RAD52SMARCA2MAPTCYP1A2CYP2C9 | |
| SCHEMBL7564114 | 0.85 | RAD52 (0.63) | RAD52SMARCA2MAPTCYP1A2CYP2C9 | |
| SCHEMBL7997888 | 0.84 | RAD52 (0.56) | RAD52SMARCA2MAPTCYP1A2CYP2C9 | |
| SCHEMBL8415115 | 0.83 | RAD52 (0.52) | RAD52SMARCA2MAPTCYP1A2CYP2C9 | |
| SCHEMBL19295821 | 0.83 | RAD52 (0.60) | RAD52SMARCA2MAPTCYP1A2CYP2C9 | |
| SCHEMBL29559676 | 0.83 | RAD52 (0.60) | RAD52SMARCA2MAPTCYP1A2CYP2C9 | |
| SCHEMBL14440022 | 0.82 | RAD52 (0.51) | RAD52SMARCA2MAPTCYP1A2CYP2C9 | |
| SCHEMBL7571817 | 0.82 | RAD52 (0.51) | RAD52SMARCA2MAPTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3058955-B1 | ANTIBODIES THAT BIND OV064 AND METHODS OF USE THEREFOR | MILLENNIUM PHARM INC (US) | 2019-05-29 | — | — | EP | claimed |
| EP-3058955-B1 | ANTIBODIES THAT BIND OV064 AND METHODS OF USE THEREFOR | MILLENNIUM PHARM INC (US) | 2019-05-29 | — | — | EP | disclosed |
| EP-1392360-B1 | MODIFIED ANTIBODIES TO PROSTATE-SPECIFIC MEMBRANE ANTIGEN AND USES THEREOF | CORNELL RES FOUNDATION INC (US) | 2011-11-30 | — | — | EP | disclosed |
| US-20100291113-A1 | Treatment of Proliferative Disorders Using Antibodies to PSMA | CORNELL UNIVERSITY (US) | 2010-11-18 | — | — | US | disclosed |