Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 5/20 | 0.51 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLR1A | O95602 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571923 | 0.94 | RAD52 (0.56) | RAD52SMARCA2ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1729642 | 0.87 | RAD52 (0.59) | RAD52SMARCA2ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8411535 | 0.86 | RAD52 (0.45) | RAD52SMARCA2ALDH1A1KDM4EMAPT | |
| SCHEMBL7564150 | 0.84 | RAD52 (0.51) | RAD52SMARCA2ALDH1A1SMN1; SMN2AOX1 | |
| SCHEMBL7566364 | 0.83 | RAD52 (0.45) | RAD52SMARCA2ALDH1A1SMN1; SMN2AOX1 | |
| SCHEMBL7566368 | 0.82 | RAD52 (0.42) | RAD52SMARCA2ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8411531 | 0.82 | RAD52 (0.42) | RAD52SMARCA2ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7564929 | 0.81 | RAD52 (0.54) | RAD52SMARCA2ALDH1A1SMN1; SMN2AOX1 | |
| SCHEMBL7568126 | 0.76 | RAD52 (0.56) | RAD52SMARCA2ALDH1A1AOX1MAPT | |
| SCHEMBL7571919 | 0.76 | RAD52 (0.50) | RAD52SMARCA2ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |