Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 16/20 | 0.73 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5483858 | 0.99 | F2R (0.74) | F2RRARARARBRARGLMNA | |
| Bromide SCHEMBL1729585 | 0.97 | F2R (0.75) | F2RRARARARBRARGLMNA | |
| Bromide SCHEMBL1732653 | 0.91 | F2R (0.61) | F2RRARARARBRARGLMNA | |
| SCHEMBL14449152 | 0.90 | F2R (0.87) | F2RMAPT | |
| Bromide SCHEMBL1730235 | 0.89 | F2R (0.87) | F2RMAPT | |
| SCHEMBL13144389 | 0.89 | F2R (0.86) | F2RMAPT | |
| Bromide SCHEMBL1732057 | 0.89 | F2R (0.62) | F2RRARARARBRARGLMNA | |
| Trifluoroacetic Acid SCHEMBL1729653 | 0.88 | F2R (0.62) | F2RRARARARBRARG | |
| SCHEMBL1732773 | 0.88 | F2R (0.84) | F2RLMNAMAPT | |
| Bromide SCHEMBL1728988 | 0.87 | F2R (0.84) | F2RLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |
| EP-1391451-A1 | 2-IMINOPYRROLIDINE DERIVATES | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |